Literature Search:
International Pharmaceutical Abstracts
International Pharmaceutical Abstracts reports a few studies of saw palmetto:
1. SAW PALMETTO: HERBAL PRESCRIPTION FOR TREATMENT OF BPH
Brown, D. J., Natural Product Research Consultants, Seattle, Washington
Drug Store News for the Pharmacist, V5, (Apr), p29-30, 1995
LANGUAGE: English
The history, mechanism of action, efficacy, dosage, and side effects of the extracts of saw palmetto (Serenoa repens; Sabal serrulata) berries for treatment of benign prostatic hyperplasia (BPH) are discussed. (10 references)
2. SAW PALMETTO SERENOA REPENS: BOTANICAL AND CHEMICAL ASPECTS
Neuzil, E.; Cousse, H., Lab. de Biochimie Med., Fac. de Med. Victor Pachon, Univ. de Bordeaux II, 146 rue Leo-Saignat, 33076 Bordeaux Cedex, France
Bulletin de la Societe de Pharmacie de Bordeaux (France), V132, (1-4), p121-141, 1993
LANGUAGE: French SUMMARY LANGUAGE: English
Botanical and chemical aspects of the saw palmetto Serenoa repens, a typical scrub palm of the Southeastern United States, are discussed, including the use of different extracts from its fruits in Europe as non-invasive therapy of benign prostatic hypertrophy and its chemical constituents. (91 references)
3. SAW PALMETTO SERENOA REPENS: PHARMACOLOGICAL ASPECTS--ITS PRESENT THERAPEUTIC USE
Neuzil, E.; Cousse, H., Lab. de Biochimie Med., Fac. de Med. Victor Pachon, Univ. de Bordeaux II, 146 rue Leo-Saignat, 33076 Bordeaux Cedex, France
Bulletin de la Societe de Pharmacie de Bordeaux (France), V132, (1-4), p142-163, 1993
LANGUAGE: French SUMMARY LANGUAGE: English
Pharmacological aspects of the saw palmetto Serenoa repens and present therapeutic uses are discussed, including use of its extracts, which interfere with sexual hormones in the treatment of prostatic benign hypertrophy. (119 references)
4. DOUBLE BLIND TRIAL OF AN EXTRACT OF THE PLANT SERENOA REPENS IN BENIGN PROSTATIC HYPERPLASIA Champault, G.; Patel, J. C.; Bonnard, A. M. Hopital Jean Verdier, 93140 Bondy, France British Journal of Clinical Pharmacology (England), V18, (Sep), p461-462, 1984 Letters CODEN: BCPHBM ISSN: 0306-5251 LANGUAGE: English RECORD TYPE: Abstract
A hexane extract of the fruit of S. repens (PA-109; Permixon) was evaluated in a placebo controlled trial in 110 outpatients with benign prostatic hyperplasia. Drug therapy was found to be more effective than placebo therapy based on subjective and objective signs. (7 references)
4. ANTI-EDEMATOUS ACTION OF AN HEXANE EXTRACT FROM SERENOA REPENS BARTR. DRUPES
Tarayre, J. P.; Delhon, A.; Lauressergues, H.; Stenger, A., Centre de Recherches Pierre Fabre, 17, ave. Jean Moulin, F 81106 Castres, France
Annales Pharmaceutiques Francaises (France), V41, (6), p559-570, 1983
LANGUAGE: French SUMMARY LANGUAGE: English
Pharmacological studies in a variety of animal models were presented to demonstrate the effects of Serenoa repens hexane extracts on induced edema. (21 references)
5. COMPOSITION OF THE HEXANE EXTRACT FROM SERENOA REPENS BARTRAM FRUITS
Hatinguais, P.; Belle, R.; Basso, Y.; Ribet, J. P.; Bauer, M.; et al Ctr. de Recherche Pierre Fabre, 17, Ave. Jean Moulin, 81106 Castres, France Trav. Soc. Pharm. Montpellier, V41, (4), p253-262, 1981
LANGUAGE: French SUMMARY LANGUAGE: English
Qualitative identification of the constituents of a hexane extract from the fruits of Serenoa repens is described, based on GC, NMR and MS analysis. Compounds playing a role in the activity of the extract in functional disorders related to prostate hypertrophy were identified as beta-sitosterol, stigmasterol, campesterol, hexacosanol, octacosanol, triacontanol and cycloartenol. (21 references)
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